|Application ||WB, IHC-P, E|
|Dilution||ELISA (1:10000), IHC-P (20 µg/ml), WB (1:500-1:1000)|
|Other Names||Solute carrier family 22 member 3, Extraneuronal monoamine transporter, EMT, Organic cation transporter 3, SLC22A3, EMTH, OCT3|
|Target/Specificity||SLC22A3 Antibody detects endogenous levels of total SLC22A3 protein.|
|Reconstitution & Storage||Store at -20°C for up to one year.|
|Precautions||SLC22A3 / OCT3 Antibody (aa275-324) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Mediates potential-dependent transport of a variety of organic cations. May play a significant role in the disposition of cationic neurotoxins and neurotransmitters in the brain.|
|Cellular Location||Membrane; Multi-pass membrane protein.|
|Tissue Location||Expressed in placenta, skeletal muscle, prostate, aorta, liver, fetal lung, salivary gland, adrenal gland, kidney and brain cortex. No expression detected in spleen|
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Provided below are standard protocols that you may find useful for product applications.
Mediates potential-dependent transport of a variety of organic cations. May play a significant role in the disposition of cationic neurotoxins and neurotransmitters in the brain.
Gruendemann D.,et al.Nat. Neurosci. 1:349-351(1998).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mungall A.J.,et al.Nature 425:805-811(2003).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Verhaagh S.,et al.Genomics 55:209-218(1999).
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