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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   LCP1 / L-Plastin Antibody (clone LPL4A.1)   

LCP1 / L-Plastin Antibody (clone LPL4A.1)

Mouse Monoclonal Antibody

  • IHC - LCP1 / L-Plastin Antibody (clone LPL4A.1) ALS15817
    Anti-LCP1 / L-Plastin antibody IHC staining of human tonsil.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P13796
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names LPL4A.1
Calculated MW 70kDa
Dilution IHC-P (10 µg/ml), WB (1-2 µg/ml),
Additional Information
Gene ID 3936
Other Names Plastin-2, L-plastin, LC64P, Lymphocyte cytosolic protein 1, LCP-1, LCP1, PLS2
Target/Specificity Headpiece region
Reconstitution & Storage Stable for 24 months when stored at 2-8°C.
PrecautionsLCP1 / L-Plastin Antibody (clone LPL4A.1) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name LCP1
Synonyms PLS2
Function Actin-binding protein. Plays a role in the activation of T-cells in response to costimulation through TCR/CD3 and CD2 or CD28. Modulates the cell surface expression of IL2RA/CD25 and CD69.
Cellular Location Cytoplasm, cytoskeleton. Cell junction. Cell projection. Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Relocalizes to the immunological synapse between peripheral blood T-lymphocytes and antibody-presenting cells in response to costimulation through TCR/CD3 and CD2 or CD28. Associated with the actin cytoskeleton at membrane ruffles (By similarity). Relocalizes to actin-rich cell projections upon serine phosphorylation.
Tissue Location Detected in intestinal microvilli, hair cell stereocilia, and fibroblast filopodia, in spleen and other lymph node-containing organs. Expressed in peripheral blood T- lymphocytes, neutrophils, monocytes, B-lymphocytes, and myeloid cells.
Volume 250 µl
Research Areas
Citations (0)

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Actin-binding protein. Plays a role in the activation of T-cells in response to costimulation through TCR/CD3 and CD2 or CD28. Modulates the cell surface expression of IL2RA/CD25 and CD69.


Zu Y.,et al.Biochemistry 29:8319-8324(1990).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Dunham A.,et al.Nature 428:522-528(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Lin C.-S.,et al.Mol. Cell. Biol. 8:4659-4668(1988).

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$ 450.00
Cat# ALS15817
(40 western blots)
Availability: 5 days
Bulk Size
Seasonal Special on Bulk Order
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