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ADAM19 Antibody
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P |
|---|---|
| Primary Accession | Q9H013 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 105kDa |
| Dilution | IHC-P (5 µg/ml), WB (1:250), |
| Gene ID | 8728 |
|---|---|
| Other Names | Disintegrin and metalloproteinase domain-containing protein 19, ADAM 19, 3.4.24.-, Meltrin-beta, Metalloprotease and disintegrin dendritic antigen marker, MADDAM, ADAM19, MLTNB |
| Target/Specificity | Not tested with other proteins. |
| Reconstitution & Storage | Store at -20°C for up to one year. |
| Precautions | ADAM19 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ADAM19 |
|---|---|
| Synonyms | MLTNB |
| Function | Participates in the proteolytic processing of beta-type neuregulin isoforms which are involved in neurogenesis and synaptogenesis, suggesting a regulatory role in glial cell. Also cleaves alpha-2 macroglobulin. May be involved in osteoblast differentiation and/or osteoblast activity in bone (By similarity). |
| Cellular Location | Membrane; Single-pass type I membrane protein. |
| Tissue Location | Expressed in many normal organ tissues and several cancer cell lines |
| Volume | 50 µl |
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Provided below are standard protocols that you may find useful for product applications.
Background
Participates in the proteolytic processing of beta-type neuregulin isoforms which are involved in neurogenesis and synaptogenesis, suggesting a regulatory role in glial cell. Also cleaves alpha-2 macroglobulin. May be involved in osteoblast differentiation and/or osteoblast activity in bone (By similarity).
References
Wang Y.-G.,et al.Submitted (DEC-2000) to the EMBL/GenBank/DDBJ databases.
Fritsche J.,et al.Blood 96:732-739(2000).
Wei P.,et al.Biochem. Biophys. Res. Commun. 280:744-755(2001).
Schmutz J.,et al.Nature 431:268-274(2004).
Xu R.,et al.Submitted (MAR-1999) to the EMBL/GenBank/DDBJ databases.
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