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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   NRBP1 / NRBP Antibody (clone 2C8)   

NRBP1 / NRBP Antibody (clone 2C8)

Mouse Monoclonal Antibody

     
  • WB - NRBP1 / NRBP Antibody (clone 2C8) ALS15827
    HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY NRBP1...
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IP, Flo
Primary Accession Q9UHY1
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 2C8
Calculated MW 60kDa
Dilution Flo (1:100), IHC-P (10 µg/ml), WB (1:500)
Additional Information
Gene ID 29959
Other Names Nuclear receptor-binding protein, NRBP1, BCON3 {ECO:0000312|EMBL:AAF21967.1}, NRBP
Target/Specificity Human NRBP1 / MADM
Reconstitution & Storage Store at -20°C. Minimize freezing and thawing.
PrecautionsNRBP1 / NRBP Antibody (clone 2C8) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NRBP1
Synonyms BCON3 {ECO:0000312|EMBL:AAF21967.1}, NRB
Function May play a role in subcellular trafficking between the endoplasmic reticulum and Golgi apparatus through interactions with the Rho-type GTPases. Binding to the NS3 protein of dengue virus type 2 appears to subvert this activity into the alteration of the intracellular membrane structure associated with flaviviral replication.
Cellular Location Cytoplasm, cell cortex. Endomembrane system. Cell projection, lamellipodium. Note=Colocalizes with activated RAC3 to endomembranes and at the cell periphery in lamellipodia
Tissue Location Ubiquitously expressed in all tissues examined with high levels in the testis.
Volume 50 µl
Research Areas
Citations (0)

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Background

May play a role in subcellular trafficking between the endoplasmic reticulum and Golgi apparatus through interactions with the Rho-type GTPases. Binding to the NS3 protein of dengue virus type 2 appears to subvert this activity into the alteration of the intracellular membrane structure associated with flaviviral replication.

References

Hooper J.D.,et al.Genomics 66:113-118(2000).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Wiemann S.,et al.Genome Res. 11:422-435(2001).
Suzuki Y.,et al.Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
Hillier L.W.,et al.Nature 434:724-731(2005).

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$ 395.00
Cat# ALS15827
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