GSC / Goosecoid Antibody (clone 2C1)
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | P56915 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Clone Names | 2C1 |
Calculated MW | 28kDa |
Dilution | IHC-P (3-10 µg/ml) |
Gene ID | 145258 |
---|---|
Other Names | Homeobox protein goosecoid, GSC |
Target/Specificity | Human GSC |
Reconstitution & Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
Precautions | GSC / Goosecoid Antibody (clone 2C1) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | GSC |
---|---|
Function | Regulates chordin (CHRD). May play a role in spatial programing within discrete embryonic fields or lineage compartments during organogenesis. In concert with NKX3-2, plays a role in defining the structural components of the middle ear; required for the development of the entire tympanic ring (By similarity). Probably involved in the regulatory networks that define neural crest cell fate specification and determine mesoderm cell lineages in mammals. |
Cellular Location | Nucleus. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Regulates chordin (CHRD). May play a role in spatial programing within discrete embryonic fields or lineage compartments during organogenesis. In concert with NKX3-2, plays a role in defining the structural components of the middle ear; required for the development of the entire tympanic ring (By similarity). Probably involved in the regulatory networks that define neural crest cell fate specification and determine mesoderm cell lineages in mammals.
References
Blum M.,et al.Genomics 21:388-393(1994).
Guo J.H.,et al.Submitted (NOV-2002) to the EMBL/GenBank/DDBJ databases.
Parry D.A.,et al.Am. J. Hum. Genet. 93:1135-1142(2013).
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.