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GSC / Goosecoid Antibody (clone 2C1)

Mouse Monoclonal Antibody

     
  • IHC - GSC / Goosecoid Antibody (clone 2C1) ALS15831
    Anti-GSC / Goosecoid antibody IHC staining of human skin.
  • WB - GSC / Goosecoid Antibody (clone 2C1) ALS15831
    GSC monoclonal antibody (M17), clone 2C1. Western blot of GSC expression in human kidney.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession P56915
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 2C1
Calculated MW 28kDa
Dilution IHC-P (3-10 µg/ml)
Additional Information
Gene ID 145258
Other Names Homeobox protein goosecoid, GSC
Target/Specificity Human GSC
Reconstitution & Storage Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsGSC / Goosecoid Antibody (clone 2C1) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GSC
Function Regulates chordin (CHRD). May play a role in spatial programing within discrete embryonic fields or lineage compartments during organogenesis. In concert with NKX3-2, plays a role in defining the structural components of the middle ear; required for the development of the entire tympanic ring (By similarity). Probably involved in the regulatory networks that define neural crest cell fate specification and determine mesoderm cell lineages in mammals.
Cellular Location Nucleus.
Research Areas
Citations (0)

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Background

Regulates chordin (CHRD). May play a role in spatial programing within discrete embryonic fields or lineage compartments during organogenesis. In concert with NKX3-2, plays a role in defining the structural components of the middle ear; required for the development of the entire tympanic ring (By similarity). Probably involved in the regulatory networks that define neural crest cell fate specification and determine mesoderm cell lineages in mammals.

References

Blum M.,et al.Genomics 21:388-393(1994).
Guo J.H.,et al.Submitted (NOV-2002) to the EMBL/GenBank/DDBJ databases.
Parry D.A.,et al.Am. J. Hum. Genet. 93:1135-1142(2013).

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$ 450.00
Cat# ALS15831
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