|Application ||WB, IHC-P, IF, Flo|
|Reactivity||Human, Mouse, Monkey|
|Dilution||Flo (1:100), IF (1:50-1:100), IHC-P (1:150), WB (1:500-1:2000) ,|
|Other Names||Phosphoglycerate mutase 2, 18.104.22.168, 22.214.171.124, 126.96.36.199, BPG-dependent PGAM 2, Muscle-specific phosphoglycerate mutase, Phosphoglycerate mutase isozyme M, PGAM-M, PGAM2, PGAMM|
|Reconstitution & Storage||Store at -20°C. Minimize freezing and thawing.|
|Precautions||PGAM2 Antibody (clone 4E9) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Interconversion of 3- and 2-phosphoglycerate with 2,3- bisphosphoglycerate as the primer of the reaction. Can also catalyze the reaction of EC 188.8.131.52 (synthase) and EC 184.108.40.206 (phosphatase), but with a reduced activity.|
|Tissue Location||In mammalian tissues there are two types of phosphoglycerate mutase isozymes: type-M in muscles and type-B in other tissues|
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Provided below are standard protocols that you may find useful for product applications.
Interconversion of 3- and 2-phosphoglycerate with 2,3- bisphosphoglycerate as the primer of the reaction. Can also catalyze the reaction of EC 220.127.116.11 (synthase) and EC 18.104.22.168 (phosphatase), but with a reduced activity.
Castella-Escola J.,et al.Gene 91:225-232(1990).
Tsujino S.,et al.J. Biol. Chem. 264:15334-15337(1989).
Shanske S.,et al.J. Biol. Chem. 262:14612-14617(1987).
Denis N.J.,et al.Proteomics 7:868-874(2007).
Tsujino S.,et al.Am. J. Hum. Genet. 52:472-477(1993).
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