|Application ||WB, IHC-P, E|
|Reactivity||Human, Mouse, Rat|
|Other Names||Thymidylate synthase, TS, TSase, 22.214.171.124, TYMS, TS|
|Target/Specificity||Recognizes human Thymidylate Synthase and is useful in determining its presence in various assays. Because inhibition of Thymidylate Synthase prevents DNA synthesis and cell proliferation, the enzyme is an important target for cancer chemotherapeutic ...|
|Reconstitution & Storage||Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.|
|Precautions||TS / Thymidylate Synthase Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Contributes to the de novo mitochondrial thymidylate biosynthesis pathway.|
|Cellular Location||Nucleus. Cytoplasm. Mitochondrion. Mitochondrion matrix. Mitochondrion inner membrane|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Contributes to the de novo mitochondrial thymidylate biosynthesis pathway.
Takeishi K.,et al.Nucleic Acids Res. 13:2035-2043(1985).
Kaneda S.,et al.J. Biol. Chem. 265:20277-20284(1990).
Hisatomi H.,et al.Cancer Lett. 193:127-131(2003).
Shichijo S.,et al.Submitted (MAY-2001) to the EMBL/GenBank/DDBJ databases.
Nusbaum C.,et al.Nature 437:551-555(2005).
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