|Application ||WB, IHC-P, E|
|Reactivity||Human, Mouse, Rat, Hamster, Monkey, Pig, Horse, Bovine|
|Dilution||ELISA (1:32000), IHC-P (5 µg/ml), WB (1:32000)|
|Other Names||Proteasome activator complex subunit 2, 11S regulator complex subunit beta, REG-beta, Activator of multicatalytic protease subunit 2, Proteasome activator 28 subunit beta, PA28b, PA28beta, PSME2|
|Reconstitution & Storage||Store at -20°C. Minimize freezing and thawing.|
|Precautions||PSME2 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Implicated in immunoproteasome assembly and required for efficient antigen processing. The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome.|
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Provided below are standard protocols that you may find useful for product applications.
Implicated in immunoproteasome assembly and required for efficient antigen processing. The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome.
McCusker D.,et al.Immunogenetics 49:438-445(1999).
Ahn J.Y.,et al.FEBS Lett. 366:37-42(1995).
Heilig R.,et al.Nature 421:601-607(2003).
Bienvenut W.V.,et al.Submitted (OCT-2004) to UniProtKB.
Wang X.,et al.Biochemistry 46:3553-3565(2007).
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