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DESI2 / PPPDE1 Antibody (Internal)
Goat Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | Q9BSY9 |
| Reactivity | Human, Mouse, Rat, Rabbit, Hamster, Monkey, Pig, Chicken, Horse, Xenopus, Bovine, Dog |
| Host | Goat |
| Clonality | Polyclonal |
| Calculated MW | 21kDa |
| Dilution | ELISA (1:32000), IHC-P (10 µg/ml), WB (0.5-1 µg/ml) |
| Gene ID | 51029 |
|---|---|
| Other Names | Desumoylating isopeptidase 2, DeSI-2, 3.4.-.-, PPPDE peptidase domain-containing protein 1, Protein FAM152A, DESI2, C1orf121, FAM152A, PPPDE1 |
| Target/Specificity | Human PPPDE1 / C1orf121. |
| Reconstitution & Storage | Store at -20°C. Minimize freezing and thawing. |
| Precautions | DESI2 / PPPDE1 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | DESI2 |
|---|---|
| Function | Has deubiquitinating activity towards 'Lys-48'- and 'Lys-63'- linked polyubiquitin chains. Deubiquitinates 'Lys-48'-linked polyubiquitination of RPS7 leading to its stabilization (PubMed:28483520). Exhibits palmitoyl protein thioesterase (S- depalmitoylation) activity towards synthetic substrates 4- methylumbelliferyl-6-S-palmitoyl-beta-D-glucopyranoside and S- depalmitoylation probe 5 (DPP-5) (PubMed:35427157). |
| Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:Q9D291}. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Protease which may deconjugate SUMO from some substrate proteins.
References
Yu W.-Q.,et al.Submitted (FEB-2000) to the EMBL/GenBank/DDBJ databases.
Lai C.-H.,et al.Genome Res. 10:703-713(2000).
Gregory S.G.,et al.Nature 441:315-321(2006).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Burkard T.R.,et al.BMC Syst. Biol. 5:17-17(2011).
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