|Application ||IHC-P, E|
|Reactivity||Human, Mouse, Rat, Rabbit, Monkey, Horse, Bovine, Guinea Pig, Dog|
|Dilution||ELISA (1:64000), IHC-P (5 µg/ml),|
|Other Names||Zinc finger protein ZIC 3, Zinc finger protein 203, Zinc finger protein of the cerebellum 3, ZIC3, ZNF203|
|Target/Specificity||Human ZIC3. This antibody is expected to NOT cross-react with other ZIC proteins.|
|Reconstitution & Storage||Store at -20°C. Minimize freezing and thawing.|
|Precautions||ZIC3 Antibody (aa178-189) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Acts as transcriptional activator. Required in the earliest stages in both axial midline development and left-right (LR) asymmetry specification. Binds to the minimal GLI-consensus sequence 5'-GGGTGGTC-3'.|
|Cellular Location||Nucleus. Cytoplasm. Note=Localizes in the cytoplasm in presence of MDFIC overexpression (By similarity). Translocation to the nucleus requires KPNA1 or KPNA6.|
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Acts as transcriptional activator. Required in the earliest stages in both axial midline development and left-right (LR) asymmetry specification. Binds to the minimal GLI-consensus sequence 5'-GGGTGGTC-3'.
Gebbia M.,et al.Nat. Genet. 17:305-308(1997).
Salichs E.,et al.PLoS Genet. 5:E1000397-E1000397(2009).
Ross M.T.,et al.Nature 434:325-337(2005).
Zhu L.,et al.Hum. Mutat. 29:99-105(2008).
Bedard J.E.,et al.PLoS ONE 6:E23755-E23755(2011).
If you have any additional inquiries please email technical services at firstname.lastname@example.org.