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ZIC3 Antibody (aa178-189)

Goat Polyclonal Antibody

     
  • IHC - ZIC3 Antibody (aa178-189) ALS15859
    Anti-ZIC3 antibody IHC staining of human prostate.
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  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, E
Primary Accession O60481
Reactivity Human, Mouse, Rat, Rabbit, Monkey, Horse, Bovine, Guinea Pig, Dog
Host Goat
Clonality Polyclonal
Calculated MW 51kDa
Dilution ELISA (1:64000), IHC-P (5 µg/ml),
Additional Information
Gene ID 7547
Other Names Zinc finger protein ZIC 3, Zinc finger protein 203, Zinc finger protein of the cerebellum 3, ZIC3, ZNF203
Target/Specificity Human ZIC3. This antibody is expected to NOT cross-react with other ZIC proteins.
Reconstitution & Storage Store at -20°C. Minimize freezing and thawing.
PrecautionsZIC3 Antibody (aa178-189) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ZIC3
Synonyms ZNF203
Function Acts as a transcriptional activator. Required in the earliest stages in both axial midline development and left-right (LR) asymmetry specification. Binds to the minimal GLI-consensus sequence 5'-GGGTGGTC- 3'.
Cellular Location Nucleus. Cytoplasm. Note=Localizes in the cytoplasm in presence of MDFIC overexpression (By similarity) Translocation to the nucleus requires KPNA1 or KPNA6.
Research Areas
Citations (0)
citation

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Background

Acts as transcriptional activator. Required in the earliest stages in both axial midline development and left-right (LR) asymmetry specification. Binds to the minimal GLI-consensus sequence 5'-GGGTGGTC-3'.

References

Gebbia M.,et al.Nat. Genet. 17:305-308(1997).
Salichs E.,et al.PLoS Genet. 5:E1000397-E1000397(2009).
Ross M.T.,et al.Nature 434:325-337(2005).
Zhu L.,et al.Hum. Mutat. 29:99-105(2008).
Bedard J.E.,et al.PLoS ONE 6:E23755-E23755(2011).

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$ 467.50
Cat# ALS15859
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