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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >   ZIC3 Antibody (aa178-189)   

ZIC3 Antibody (aa178-189)

Goat Polyclonal Antibody

     
  • IHC - ZIC3 Antibody (aa178-189) ALS15859
    Anti-ZIC3 antibody IHC staining of human prostate.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, E
Primary Accession O60481
Reactivity Human, Mouse, Rat, Rabbit, Monkey, Horse, Bovine, Guinea Pig, Dog
Host Goat
Clonality Polyclonal
Calculated MW 51kDa
Dilution ELISA (1:64000), IHC-P (5 µg/ml),
Additional Information
Gene ID 7547
Other Names Zinc finger protein ZIC 3, Zinc finger protein 203, Zinc finger protein of the cerebellum 3, ZIC3, ZNF203
Target/Specificity Human ZIC3. This antibody is expected to NOT cross-react with other ZIC proteins.
Reconstitution & Storage Store at -20°C. Minimize freezing and thawing.
PrecautionsZIC3 Antibody (aa178-189) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ZIC3
Synonyms ZNF203
Function Acts as transcriptional activator. Required in the earliest stages in both axial midline development and left-right (LR) asymmetry specification. Binds to the minimal GLI-consensus sequence 5'-GGGTGGTC-3'.
Cellular Location Nucleus. Cytoplasm. Note=Localizes in the cytoplasm in presence of MDFIC overexpression (By similarity). Translocation to the nucleus requires KPNA1 or KPNA6.
Research Areas
Citations (0)

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Background

Acts as transcriptional activator. Required in the earliest stages in both axial midline development and left-right (LR) asymmetry specification. Binds to the minimal GLI-consensus sequence 5'-GGGTGGTC-3'.

References

Gebbia M.,et al.Nat. Genet. 17:305-308(1997).
Salichs E.,et al.PLoS Genet. 5:E1000397-E1000397(2009).
Ross M.T.,et al.Nature 434:325-337(2005).
Zhu L.,et al.Hum. Mutat. 29:99-105(2008).
Bedard J.E.,et al.PLoS ONE 6:E23755-E23755(2011).

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$ 395.00
Cat# ALS15859
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