|Application ||WB, IHC-P, IF, E|
|Reactivity||Human, Mouse, Rat|
|Dilution||IF (20 µg/ml), IHC-P (5 µg/ml), WB (1 µg/ml)|
|Other Names||Transmembrane protein 204, Claudin-like protein 24, TMEM204, C16orf30, CLP24|
|Target/Specificity||Human TMEM204. At least two isoforms of TMEM204 are known to exist; this antibody will recognize both isoforms.|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.|
|Precautions||TMEM204 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Can influence paracellular permeability. Appears to be involved in cell-cell interactions through adherens.|
|Cellular Location||Cell junction, adherens junction. Cell membrane; Multi-pass membrane protein. Note=Colocalizes with the beta- catenin adherins|
|Tissue Location||Highly expressed in lung, heart, kidney and placenta. Lower expression in thymus, spleen, liver, testis and ovary. Expressed in endothelial and restricted epithelial cell populations.|
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Can influence paracellular permeability. Appears to be involved in cell-cell interactions through adherens.
Kearsey J.,et al.Eur. J. Biochem. 271:2584-2592(2004).
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Daniels R.J.,et al.Hum. Mol. Genet. 10:339-352(2001).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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