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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   NPPA / ANP Antibody (C-Terminus)   

NPPA / ANP Antibody (C-Terminus)

Goat Polyclonal Antibody

     
  • IHC - NPPA / ANP Antibody (C-Terminus) ALS15863
    Anti-NPPA / ANP antibody IHC staining of human heart.
  • WB - NPPA / ANP Antibody (C-Terminus) ALS15863
    NPPA antibody (0.01 ug/ml) staining of Mouse Heart lysate (35 ug protein in RIPA buffer).
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession P01160
Reactivity Human, Mouse, Rat, Rabbit, Hamster, Monkey, Sheep, Horse, Bovine, Dog
Host Goat
Clonality Polyclonal
Calculated MW 17kDa
Dilution ELISA (1:32000), IHC-P (5 µg/ml), WB (0.01-0.03 µg/ml)
Additional Information
Gene ID 4878
Other Names Natriuretic peptides A, CDD-ANF, Cardiodilatin, CDD, Cardiodilatin-related peptide, CDP, Prepronatriodilatin, Atrial natriuretic factor, ANF, Atrial natriuretic peptide, ANP, NPPA, ANP, PND
Target/Specificity Human NPPA. The immunizing peptide represents aa137-150 of the precursor NPPA.
Reconstitution & Storage Store at -20°C. Minimize freezing and thawing.
PrecautionsNPPA / ANP Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NPPA
Synonyms ANP, PND
Function Hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3.
Cellular Location Secreted.
Research Areas
Citations (0)

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Background

Hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3.

References

Oikawa S.,et al.Nature 309:724-726(1984).
Nakayama K.,et al.Nature 310:699-701(1984).
Nemer M.,et al.Nature 312:654-656(1984).
Greenberg B.D.,et al.Nature 312:656-658(1984).
Seidman C.E.,et al.Science 226:1206-1209(1984).

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$ 395.00
Cat# ALS15863
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