|Application ||WB, IHC-P, E|
|Reactivity||Human, Mouse, Rat|
|Dilution||IHC-P (5 µg/ml), WB (1-2 µg/ml),|
|Other Names||Ankyrin repeat and LEM domain-containing protein 1, Ankyrin repeat domain-containing protein 41, LEM-domain containing protein 3, ANKLE1, ANKRD41, LEM3|
|Target/Specificity||Human ANKLE1. Two isoforms of ANKLE1 are known to exist. ANKLE1 antibody is predicted to not cross-react with ANKLE2|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.|
|Precautions||ANKLE1 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Endonuclease that probably plays a role in the DNA damage response and DNA repair.|
|Cellular Location||Cytoplasm. Nucleus Note=At the steady state, localizes predominantly in the cytoplasm.|
|Tissue Location||Expression is predominant in adult bone marrow.|
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Provided below are standard protocols that you may find useful for product applications.
Brachner A.,et al.Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Grimwood J.,et al.Nature 428:529-535(2004).
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