|Application ||WB, IHC-P, E|
|Dilution||IHC-P (10 µg/ml), WB (1:1000),|
|Other Names||GTP-binding protein SAR1b, GTP-binding protein B, GTBPB, SAR1B, SARA2, SARB|
|Target/Specificity||Human SARA2 / SAR1B|
|Reconstitution & Storage||Can be stored at 4°C. For long term storage, aliquot and store at -20°C. Avoid repeated freezing and thawing cycles.|
|Precautions||SARA2 / SAR1B Antibody (clone AT1C7) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Activated by the guanine nucleotide exchange factor PREB. Involved in the selection of the protein cargo and the assembly of the COPII coat complex.|
|Cellular Location||Endoplasmic reticulum membrane; Peripheral membrane protein. Golgi apparatus, Golgi stack membrane; Peripheral membrane protein. Note=Associated with the endoplasmic reticulum and Golgi stacks, in particular in the juxta-nuclear Golgi region.|
|Tissue Location||Expressed in many tissues including small intestine, liver, muscle and brain|
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Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Activated by the guanine nucleotide exchange factor PREB. Involved in the selection of the protein cargo and the assembly of the COPII coat complex.
Song H.,et al.Submitted (SEP-1998) to the EMBL/GenBank/DDBJ databases.
Zhou Y.,et al.Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases.
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Burkard T.R.,et al.BMC Syst. Biol. 5:17-17(2011).
Jones B.,et al.Nat. Genet. 34:29-31(2003).
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