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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   CAPG Antibody   

CAPG Antibody

Rabbit Polyclonal Antibody

     
  • IHC - CAPG Antibody ALS15892
    Human Lung, Macrophages: Formalin-Fixed, Paraffin-Embedded (FFPE)
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession P40121
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 38kDa
Dilution ELISA (1:10000), IHC-P (2.5 µg/ml), WB (1:250)
Additional Information
Gene ID 822
Other Names Macrophage-capping protein, Actin regulatory protein CAP-G, CAPG, AFCP, MCP
Target/Specificity CAPG antibody detects endogenous levels of CAPG protein. Not tested with other proteins.
Reconstitution & Storage Store at -20°C for up to one year.
PrecautionsCAPG Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CAPG
Synonyms AFCP, MCP
Function Calcium-sensitive protein which reversibly blocks the barbed ends of actin filaments but does not sever preformed actin filaments. May play an important role in macrophage function. May play a role in regulating cytoplasmic and/or nuclear structures through potential interactions with actin. May bind DNA.
Cellular Location Nucleus. Cytoplasm. Secreted {ECO:0000250|UniProtKB:P24452}. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:17081065). Redistributes throughout the cytoplasm during mitosis and is excluded from regions containing chromosomes (By similarity). {ECO:0000250|UniProtKB:P24452, ECO:0000269|PubMed:17081065}
Tissue Location Macrophages and macrophage-like cells.
Volume 50 µl
Research Areas
Citations (0)

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Background

Calcium-sensitive protein which reversibly blocks the barbed ends of actin filaments but does not sever preformed actin filaments. May play an important role in macrophage function. May play a role in regulating cytoplasmic and/or nuclear structures through potential interactions with actin. May bind DNA.

References

Dabiri G.A.,et al.J. Biol. Chem. 267:16545-16552(1992).
Suzuki Y.,et al.Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
Hillier L.W.,et al.Nature 434:724-731(2005).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Mishra V.S.,et al.Genomics 23:560-565(1994).

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$ 395.00
Cat# ALS15892
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