|Application ||WB, IHC-P, E|
|Reactivity||Human, Mouse, Rat|
|Dilution||ELISA (1:40000), IHC-P (10 µg/ml), WB (1:500-1:1000)|
|Other Names||E3 ubiquitin-protein ligase MARCH3, 6.3.2.-, Membrane-associated RING finger protein 3, Membrane-associated RING-CH protein III, MARCH-III, RING finger protein 173, MARCH3, RNF173|
|Target/Specificity||MARCH3 Antibody detects endogenous levels of total MARCH3 protein.|
|Reconstitution & Storage||Store at -20°C for up to one year.|
|Precautions||MARCH3 Antibody (aa111-160) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||E3 ubiquitin-protein ligase which may be involved in endosomal trafficking. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.|
|Cellular Location||Cytoplasmic vesicle membrane; Multi-pass membrane protein. Early endosome membrane; Multi-pass membrane protein|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
E3 ubiquitin-protein ligase which may be involved in endosomal trafficking. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates (By similarity).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Schmutz J.,et al.Nature 431:268-274(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Fukuda H.,et al.J. Biochem. 139:137-145(2006).
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