RABEP2 Antibody (aa353-402)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | Q9H5N1 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 64kDa |
Dilution | ELISA (1:10000), IHC-P (10 µg/ml), WB (1:500-1:1000) |
Gene ID | 79874 |
---|---|
Other Names | Rab GTPase-binding effector protein 2, Rabaptin-5beta, RABEP2, RABPT5B |
Target/Specificity | RABEP2 Antibody detects endogenous levels of total RABEP2 protein. |
Reconstitution & Storage | Store at -20°C for up to one year. |
Precautions | RABEP2 Antibody (aa353-402) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | RABEP2 |
---|---|
Synonyms | RABPT5B |
Function | Plays a role in membrane trafficking and in homotypic early endosome fusion (PubMed:9524116). Participates in arteriogenesis by regulating vascular endothelial growth factor receptor 2/VEGFR2 cell surface expression and endosomal trafficking (PubMed:29425100). By interacting with SDCCAG8, localizes to centrosomes and plays a critical role in ciliogenesis (PubMed:27224062). |
Cellular Location | Cytoplasm. Early endosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, cilium basal body |
Volume | 50 µl |
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Provided below are standard protocols that you may find useful for product applications.
Background
Plays a role in membrane trafficking and in homotypic early endosome fusion.
References
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Gournier H.,et al.EMBO J. 17:1930-1940(1998).
Burkard T.R.,et al.BMC Syst. Biol. 5:17-17(2011).
Van Damme P.,et al.Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012).
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