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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   GAK Antibody (aa101-150)   

GAK Antibody (aa101-150)

Rabbit Polyclonal Antibody

     
  • WB - GAK Antibody (aa101-150) ALS15952
    Western blot of extracts from 293 cells, using GAK Antibody.
  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession O14976
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Calculated MW 143kDa
Dilution ELISA (1:5000), IHC-P (20 µg/ml), WB (1:500-1:1000)
Additional Information
Gene ID 2580
Other Names Cyclin-G-associated kinase, 2.7.11.1, GAK
Target/Specificity GAK Antibody detects endogenous levels of total GAK protein.
Reconstitution & Storage Store at -20°C for up to one year.
PrecautionsGAK Antibody (aa101-150) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GAK
Function Associates with cyclin G and CDK5. Seems to act as an auxilin homolog that is involved in the uncoating of clathrin- coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1.
Cellular Location Cytoplasm, perinuclear region. Golgi apparatus, trans-Golgi network. Cell junction, focal adhesion. Note=Localizes to the perinuclear area and to the trans-Golgi network. Also seen on the plasma membrane, probably at focal adhesions
Tissue Location Ubiquitous. Highest in testis.
Volume 50 µl
Research Areas
Citations (0)

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Background

Associates with cyclin G and CDK5. Seems to act as an auxilin homolog that is involved in the uncoating of clathrin- coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1.

References

Kimura S.H.,et al.Genomics 44:179-187(1997).
Greener T.,et al.J. Biol. Chem. 275:1365-1370(2000).
Daub H.,et al.Mol. Cell 31:438-448(2008).
Dephoure N.,et al.Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
Gauci S.,et al.Anal. Chem. 81:4493-4501(2009).

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$ 395.00
Cat# ALS15952
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