FASTKD1 Antibody (aa561-610)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
---|---|
Primary Accession | Q53R41 |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 97kDa |
Dilution | ELISA (1:10000), IHC-P (10 µg/ml), WB (1:500-1:1000) |
Gene ID | 79675 |
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Other Names | FAST kinase domain-containing protein 1, FASTKD1, KIAA1800 |
Target/Specificity | FAKD1 Antibody detects endogenous levels of total FAKD1 protein. |
Reconstitution & Storage | Store at -20°C for up to one year. |
Precautions | FASTKD1 Antibody (aa561-610) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | FASTKD1 |
---|---|
Synonyms | KIAA1800 |
Function | Involved in the down-regulation of mitochondrial MT-ND3 mRNA levels which leads to decreased respiratory complex I abundance and activity. |
Cellular Location | Mitochondrion Note=Preferentially localizes to mitochondrial RNA granules, platforms for post-transcriptional RNA modification and ribosome assembly (PubMed:28335001). |
Tissue Location | Expression detected in spleen, thymus, testis, ovary, colon, heart, smooth muscle, kidney, brain, lung, liver and white adipose tissue with highest expression in heart |
Volume | 50 µl |
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Provided below are standard protocols that you may find useful for product applications.
References
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hillier L.W.,et al.Nature 434:724-731(2005).
Nagase T.,et al.DNA Res. 8:85-95(2001).
Choudhary C.,et al.Science 325:834-840(2009).
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