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>   home   >   Products   >   Primary Antibodies   >   HSPA5 / GRP78 / BiP Antibody (aa645-654)   

HSPA5 / GRP78 / BiP Antibody (aa645-654)

Rabbit Polyclonal Antibody

     
  • IHC - HSPA5 / GRP78 / BiP Antibody (aa645-654) ALS15990
    Anti-HSPA5 / GRP78 / BIP antibody IHC staining of human brain, cortex.
  • IHC - HSPA5 / GRP78 / BiP Antibody (aa645-654) ALS15990
    Anti-HSPA5 / GRP78 / BIP antibody IHC staining of human placenta.
  • WB - HSPA5 / GRP78 / BiP Antibody (aa645-654) ALS15990
    Grp78 (Bip), Rat tissue Mix, polyclonal.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P
Primary Accession P11021
Reactivity Human, Mouse, Rat, Rabbit, Hamster, Monkey, Xenopus, Bovine
Host Rabbit
Clonality Polyclonal
Calculated MW 72kDa
Dilution IHC-P (1:100), WB (1:2000),
Additional Information
Gene ID 3309
Other Names 78 kDa glucose-regulated protein, GRP-78, Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78, Heat shock 70 kDa protein 5, Immunoglobulin heavy chain-binding protein, BiP, HSPA5, GRP78
Target/Specificity Detects a protein with a mass of ~78 kD corresponding to Grp78.
Reconstitution & Storage Store at -20°C.
PrecautionsHSPA5 / GRP78 / BiP Antibody (aa645-654) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HSPA5
Synonyms GRP78
Function Probably plays a role in facilitating the assembly of multimeric protein complexes inside the endoplasmic reticulum. Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10, probably to facilitate the release of DNAJC10 from its substrate.
Cellular Location Endoplasmic reticulum lumen. Melanosome. Cytoplasm Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV
Volume 50 µl
Citations (0)

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Background

Probably plays a role in facilitating the assembly of multimeric protein complexes inside the endoplasmic reticulum. Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10, probably to facilitate the release of DNAJC10 from its substrate.

References

Ting J.,et al.DNA 7:275-286(1988).
Chao C.C.K.,et al.Submitted (DEC-1995) to the EMBL/GenBank/DDBJ databases.
Hansen J.J.,et al.Submitted (JAN-2000) to the EMBL/GenBank/DDBJ databases.
Bermudez-Fajardo A.,et al.Submitted (DEC-1999) to the EMBL/GenBank/DDBJ databases.
Humphray S.J.,et al.Nature 429:369-374(2004).

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$ 395.00
Cat# ALS15990
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