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>   home   >   Products   >   Primary Antibodies   >   Immunology   >   SSB / La Antibody (clone 1E11)   

SSB / La Antibody (clone 1E11)

Mouse Monoclonal Antibody

     
  • IF - SSB / La Antibody (clone 1E11) ALS15993
    Immunofluorescent staining of HepG2 cells using anti-SSB mouse monoclonal antibody.
  • IHC - SSB / La Antibody (clone 1E11) ALS15993
    Anti-SSB / La antibody IHC staining of human prostate.
  • WB - SSB / La Antibody (clone 1E11) ALS15993
    HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SSB...
  • WB - SSB / La Antibody (clone 1E11) ALS15993
    Western blot of extracts (35 ug) from 9 different cell lines by using anti-SSB monoclonal antibody.
  • IF - SSB / La Antibody (clone 1E11) ALS15993
    Anti-SSB mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently...
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, IP, Flo
Primary Accession P05455
Reactivity Human, Mouse, Rat, Monkey, Dog
Host Mouse
Clonality Monoclonal
Clone Names 1E11
Calculated MW 47kDa
Dilution Flo (1:100), IF (1:50-1:100), IHC-P (10 µg/ml), WB (1:1000-1:2000) ,
Additional Information
Gene ID 6741
Other Names Lupus La protein, La autoantigen, La ribonucleoprotein, Sjoegren syndrome type B antigen, SS-B, SSB
Target/Specificity Human SSB / La
Reconstitution & Storage Store at -20°C. Minimize freezing and thawing.
PrecautionsSSB / La Antibody (clone 1E11) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SSB
Function Binds to the 3' poly(U) terminus of nascent RNA polymerase III transcripts, protecting them from exonuclease digestion and facilitating their folding and maturation (PubMed:3192525, PubMed:2470590). In case of Coxsackievirus B3 infection, binds to the viral internal ribosome entry site (IRES) and stimulates the IRES-mediated translation (PubMed:12384597).
Cellular Location Nucleus.
Volume 50 µl
Research Areas
Citations (0)

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Background

Binds to the 3' poly(U) terminus of nascent RNA polymerase III transcripts, protecting them from exonuclease digestion and facilitating their folding and maturation.

References

Chan E.K.L.,et al.Nucleic Acids Res. 17:2233-2244(1989).
Chambers J.C.,et al.J. Biol. Chem. 263:18043-18051(1988).
Kalnine N.,et al.Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases.
Goshima N.,et al.Nat. Methods 5:1011-1017(2008).
Hillier L.W.,et al.Nature 434:724-731(2005).

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$ 395.00
Cat# ALS15993
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