|Application ||WB, IF, E, IHC-Fr|
|Reactivity||Human, Mouse, Rat|
|Dilution||IF (10 µg/ml), IHC-Fr (1:50),|
|Other Names||Golgi resident protein GCP60, Acyl-CoA-binding domain-containing protein 3, Golgi complex-associated protein 1, GOCAP1, Golgi phosphoprotein 1, GOLPH1, PBR- and PKA-associated protein 7, Peripheral benzodiazepine receptor-associated protein PAP7, ACBD3, GCP60, GOCAP1, GOLPH1|
|Reconstitution & Storage||Store at -20°C. Aliquot to avoid freeze/thaw cycles.|
|Precautions||GCP60 / ACBD3 Antibody (clone 2G2) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||GCP60, GOCAP1, GOLPH1|
|Function||Involved in the maintenance of Golgi structure by interacting with giantin, affecting protein transport between the endoplasmic reticulum and Golgi. Involved in hormone-induced steroid biosynthesis in testicular Leydig cells (By similarity).|
|Cellular Location||Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Mitochondrion. Note=Also mitochondrial (via its interaction with PBR).|
|Tissue Location||Ubiquitous, with highest expression in testis and ovary.|
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Involved in the maintenance of Golgi structure by interacting with giantin, affecting protein transport between the endoplasmic reticulum and Golgi. Involved in hormone-induced steroid biosynthesis in testicular Leydig cells (By similarity).
Sohda M.,et al.J. Biol. Chem. 276:45298-45306(2001).
Liu J.,et al.Submitted (SEP-2002) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Gregory S.G.,et al.Nature 441:315-321(2006).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
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