|Application ||WB, IF, IHC-Fr, Flo|
|Reactivity||Human, Mouse, Zebrafish, Hamster, Pig, Xenopus|
|Dilution||Flo (1:100-1:200), IHC-Fr (1:100), WB (1:100-1:1000)|
|Other Names||Lamin-B2, LMNB2, LMN2|
|Target/Specificity||Reacts with an epitope located in the C-terminal part of lamin B2.|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.|
|Precautions||Lamin B2 Antibody (clone LN43) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin.|
|Cellular Location||Nucleus inner membrane; Lipid-anchor; Nucleoplasmic side|
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Provided below are standard protocols that you may find useful for product applications.
Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin.
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Grimwood J.,et al.Nature 428:529-535(2004).
Lubec G.,et al.Submitted (DEC-2008) to UniProtKB.
Biamonti G.,et al.Mol. Cell. Biol. 12:3499-3506(1992).
Olsen J.V.,et al.Cell 127:635-648(2006).
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