|Application ||WB, IHC-P, E|
|Dilution||IHC-P (10 µg/ml), WB (1-2 µg/ml),|
|Other Names||Reticulon-4 receptor-like 2, Nogo receptor-like 3, Nogo-66 receptor homolog 1, Nogo-66 receptor-related protein 2, NgR2, RTN4RL2 (HGNC:23053)|
|Target/Specificity||Three alternatively spliced transcript variants have been observed. RTN4RL2 antibody is predicted to not cross-react with other Nogo receptor-like proteins.|
|Reconstitution & Storage||Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.|
|Precautions||RTN4RL2 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May play a role in regulating axonal regeneration and plasticity in the adult central nervous system.|
|Cellular Location||Cell membrane; Lipid-anchor, GPI-anchor Note=Localized to the surface of neurons, including axons|
|Tissue Location||Highly expressed in brain and liver. Expressed at lower levels in kidney, mammary gland, placenta, skeletal muscle, spleen and thyroid.|
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May play a role in regulating axonal regeneration and plasticity in the adult central nervous system.
Pignot V.,et al.J. Neurochem. 85:717-728(2003).
Lauren J.,et al.Mol. Cell. Neurosci. 24:581-594(2003).
Rader C.,et al.Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
Taylor T.D.,et al.Nature 440:497-500(2006).
Barton W.A.,et al.EMBO J. 22:3291-3302(2003).
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