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CRB1 Antibody (Internal)

Rabbit Polyclonal Antibody

     
  • IHC - CRB1 Antibody (Internal) ALS16003
    Anti-CRB1 antibody IHC staining of human skeletal muscle.
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  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession P82279
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 154kDa
Dilution IHC-P (10 µg/ml), WB (1-2 µg/ml),
Additional Information
Gene ID 23418
Other Names Protein crumbs homolog 1, CRB1
Target/Specificity Alternatively spliced transcript variants have been observed. CRB1 antibody is predicted to not cross-react with CRB2.
Reconstitution & Storage Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
PrecautionsCRB1 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CRB1 (HGNC:2343)
Function Plays a role in photoreceptor morphogenesis in the retina (By similarity). May maintain cell polarization and adhesion (By similarity).
Cellular Location [Isoform 1]: Apical cell membrane {ECO:0000250|UniProtKB:Q8VHS2}; Single-pass type I membrane protein. Secreted. Cell projection, cilium, photoreceptor outer segment {ECO:0000250|UniProtKB:Q8VHS2} Photoreceptor inner segment {ECO:0000250|UniProtKB:Q8VHS2}
Tissue Location Preferential expression in retina, also expressed in brain, testis, fetal brain and fetal eye (PubMed:15914641) Expressed at the outer limiting membrane and apical to adherens junctions in the retina (PubMed:15914641)
Research Areas
Citations (0)
citation

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Background

Plays a role in photoreceptor morphogenesis in the retina. May maintain cell polarization and adhesion.

References

den Hollander A.I.,et al.Nat. Genet. 23:217-221(1999).
den Hollander A.I.,et al.Hum. Mol. Genet. 10:2767-2773(2001).
Kantardzhieva A.,et al.Invest. Ophthalmol. Vis. Sci. 46:2192-2201(2005).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Ota T.,et al.Nat. Genet. 36:40-45(2004).

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$ 467.50
Cat# ALS16003
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