|Application ||WB, IHC-P, E|
|Reactivity||Human, Mouse, Rat|
|Dilution||IHC-P (10 µg/ml), WB (1-2 µg/ml),|
|Other Names||Interleukin-15, IL-15, IL15|
|Target/Specificity||At least two isoforms of IL-15 are known to exist.|
|Reconstitution & Storage||Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.|
|Precautions||IL15 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Cytokine that stimulates the proliferation of T- lymphocytes. Stimulation by IL-15 requires interaction of IL-15 with components of IL-2R, including IL-2R beta and probably IL-2R gamma but not IL-2R alpha.|
|Cellular Location||Isoform IL15-S48AA: Secreted.|
|Tissue Location||Most abundant in placenta and skeletal muscle. It is also detected in the heart, lung, liver and kidney. IL15- S21AA is preferentially expressed in tissues such as testis and thymus|
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Provided below are standard protocols that you may find useful for product applications.
Cytokine that stimulates the proliferation of T- lymphocytes. Stimulation by IL-15 requires interaction of IL-15 with components of IL-2R, including IL-2R beta and probably IL-2R gamma but not IL-2R alpha.
Grabstein K.H.,et al.Science 264:965-968(1994).
Krause H.,et al.Cytokine 8:667-674(1996).
Meazza R.,et al.Oncogene 12:2187-2192(1996).
Tagaya Y.,et al.Proc. Natl. Acad. Sci. U.S.A. 94:14444-14449(1997).
Meazza R.,et al.Submitted (APR-1997) to the EMBL/GenBank/DDBJ databases.
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