|Application ||WB, IHC-P, IF, E|
|Dilution||IF (5 µg/ml), IHC-P (10 µg/ml), WB (1 µg/ml)|
|Other Names||T-box transcription factor TBX21, T-box protein 21, T-cell-specific T-box transcription factor T-bet, Transcription factor TBLYM, TBX21, TBET, TBLYM|
|Target/Specificity||TBX21 antibody is human and mouse reactive.|
|Reconstitution & Storage||Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.|
|Precautions||TBX21 / T-bet Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Transcription factor that controls the expression of the TH1 cytokine, interferon-gamma. Initiates TH1 lineage development from naive TH precursor cells both by activating TH1 genetic programs and by repressing the opposing TH2 programs.|
|Tissue Location||T-cell specific.|
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Transcription factor that controls the expression of the TH1 cytokine, interferon-gamma. Initiates TH1 lineage development from naive TH precursor cells both by activating TH1 genetic programs and by repressing the opposing TH2 programs.
Yang S.,et al.Submitted (SEP-1998) to the EMBL/GenBank/DDBJ databases.
Szabo S.J.,et al.Cell 100:655-669(2000).
Akahoshi M.,et al.Hum. Genet. 117:16-26(2005).
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