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>   home   >   Products   >   Primary Antibodies   >   EHD2 Antibody (C-Terminus)   

EHD2 Antibody (C-Terminus)

Goat Polyclonal Antibody

     
  • WB - EHD2 Antibody (C-Terminus) ALS16073
    Antibody staining (0.003 ug/ml) of human heart lysate (RIPA buffer, 35 ug total protein per lane).
  • IHC - EHD2 Antibody (C-Terminus) ALS16073
    Anti-EHD2 antibody IHC staining of human vessel.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q9NZN4
Reactivity Human, Monkey, Bovine
Host Goat
Clonality Polyclonal
Calculated MW 61kDa
Dilution ELISA (1:32000), IHC-P (5 µg/ml), WB (1:32000)
Additional Information
Gene ID 30846
Other Names EH domain-containing protein 2, PAST homolog 2, EHD2, PAST2
Target/Specificity Human EHD2. This antibody is expected to recognise EHD1 protein as well as EHD2.
Reconstitution & Storage Store at -20°C. Minimize freezing and thawing.
PrecautionsEHD2 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name EHD2
Synonyms PAST2
Function Plays a role in membrane reorganization in response to nucleotide hydrolysis. Binds to liposomes and deforms them into tubules. Plays a role in membrane trafficking between the plasma membrane and endosomes. Important for the internalization of GLUT4. Required for normal fusion of myoblasts to skeletal muscle myotubes. Required for translocation of FER1L5 to the plasma membrane. Binds ATP; does not bind GTP (By similarity).
Cellular Location Cell membrane; Peripheral membrane protein; Cytoplasmic side. Endosome membrane; Peripheral membrane protein Note=Colocalizes with GLUT4 in intracellular tubulovesicular structures that are associated with cortical F-actin. Colocalizes with FER1L5 at plasma membrane in myoblasts and myotubes (By similarity).
Tissue Location Highly expressed in heart and moderately expressed in placenta, lung, and skeletal muscle
Citations (0)

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Background

Plays a role in membrane reorganization in response to nucleotide hydrolysis. Binds to liposomes and deforms them into tubules. Plays a role in membrane trafficking between the plasma membrane and endosomes. Important for the internalization of GLUT4. Required for normal fusion of myoblasts to skeletal muscle myotubes. Required for translocation of FER1L5 to the plasma membrane. Binds ATP; does not bind GTP (By similarity).

References

Pohl U.,et al.Genomics 63:255-262(2000).
Benjamin S.,et al.Submitted (DEC-2001) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Grimwood J.,et al.Nature 428:529-535(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.

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$ 395.00
Cat# ALS16073
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