|Application ||WB, IHC-P, E|
|Reactivity||Human, Rat, Monkey|
|Dilution||ELISA (1:2000), IHC-P (5 µg/ml), WB (1:2000)|
|Other Names||7SK snRNA methylphosphate capping enzyme, MePCE, 2.1.1.-, Bicoid-interacting protein 3 homolog, Bin3 homolog, MEPCE, BCDIN3|
|Reconstitution & Storage||Store at -20°C. Minimize freezing and thawing.|
|Precautions||MEPCE Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||S-adenosyl-L-methionine-dependent methyltransferase that adds a methylphosphate cap at the 5'-end of 7SK snRNA, leading to stabilize it.|
|Tissue Location||Expressed in chronic myeloid leukemia cells, adrenal gland, brain, cerebellum, kidney, lung, mammary gland and testis. Weakly or not expressed in other tissues|
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Provided below are standard protocols that you may find useful for product applications.
S-adenosyl-L-methionine-dependent methyltransferase that adds a methylphosphate cap at the 5'-end of 7SK snRNA, leading to stabilize it.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hillier L.W.,et al.Nature 424:157-164(2003).
Scherer S.W.,et al.Science 300:767-772(2003).
Rogers S.A.,et al.Br. J. Haematol. 119:112-114(2002).
Rush J.,et al.Nat. Biotechnol. 23:94-101(2005).
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