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>   home   >   Products   >   Primary Antibodies   >   Cardiovascular   >   GGCX Antibody (C-Terminus)   

GGCX Antibody (C-Terminus)

Goat Polyclonal Antibody

     
  • IHC - GGCX Antibody (C-Terminus) ALS16085
    Anti-GGCX antibody IHC staining of human kidney.
  • WB - GGCX Antibody (C-Terminus) ALS16085
    GGCX antibody (0.3 ug/ml) staining of Human Muscle lysate (35 ug protein in RIPA buffer).
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession P38435
Reactivity Human, Monkey
Host Goat
Clonality Polyclonal
Calculated MW 88kDa
Dilution IHC-P (5 µg/ml), WB (0.3-1 µg/ml),
Additional Information
Gene ID 2677
Other Names Vitamin K-dependent gamma-carboxylase, 4.1.1.90, Gamma-glutamyl carboxylase, Peptidyl-glutamate 4-carboxylase, Vitamin K gamma glutamyl carboxylase, GGCX, GC
Target/Specificity Human GGCX. This antibody is expected to recognize both isoforms (NP_000812.2; NP_001135741.1).
Reconstitution & Storage Store at -20°C. Minimize freezing and thawing.
PrecautionsGGCX Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GGCX
Synonyms GC
Function Mediates the vitamin K-dependent carboxylation of glutamate residues to calcium-binding gamma-carboxyglutamate (Gla) residues with the concomitant conversion of the reduced hydroquinone form of vitamin K to vitamin K epoxide.
Cellular Location Endoplasmic reticulum membrane; Multi-pass membrane protein
Research Areas
Citations (0)

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Background

Mediates the vitamin K-dependent carboxylation of glutamate residues to calcium-binding gamma-carboxyglutamate (Gla) residues with the concomitant conversion of the reduced hydroquinone form of vitamin K to vitamin K epoxide.

References

Wu S.-M.,et al.Science 254:1634-1636(1991).
Wu S.-M.,et al.Blood 89:4058-4062(1997).
Ying L.,et al.Submitted (MAR-1996) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hillier L.W.,et al.Nature 434:724-731(2005).

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$ 395.00
Cat# ALS16085
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