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NF-L / NEFL Antibody

Chicken Polyclonal Antibody

     
  • WB - NF-L / NEFL Antibody ALS16095
    Western blots of whole protein extracts of rat spinal cord (lane 1), brain stem (lane 2),...
    detail
  • ICC - NF-L / NEFL Antibody ALS16095
    View of mixed neuron/glial cultures stained with NF-L / NEFL antibody (red) and rabbit antibody...
    detail
  • IHC - NF-L / NEFL Antibody ALS16095
    Anti-NF-L / NEFL antibody IHC staining of human brain, cortex.
    detail
  • SPECIFICATION
  • CITATIONS
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  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, ICC
Primary Accession P07196
Reactivity Human
Host Chicken
Clonality Polyclonal
Calculated MW 62kDa
Dilution ICC (1:5000), IF (1:5000), IHC-P (1:500), WB (1:10000) ,
Additional Information
Gene ID 4747
Other Names Neurofilament light polypeptide, NF-L, 68 kDa neurofilament protein, Neurofilament triplet L protein, NEFL, NF68, NFL
Target/Specificity Human NF-L / NEFL
Reconstitution & Storage +4°C or -20°C, Avoid repeated freezing and thawing.
PrecautionsNF-L / NEFL Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NEFL
Synonyms NF68, NFL
Function Neurofilaments usually contain three intermediate filament proteins: NEFL, NEFM, and NEFH which are involved in the maintenance of neuronal caliber. May additionally cooperate with the neuronal intermediate filament proteins PRPH and INA to form neuronal filamentous networks (By similarity).
Cellular Location Cell projection, axon {ECO:0000250|UniProtKB:P08551}. Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:P08551}
Volume 50 µl
Research Areas
Citations (0)
citation

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Background

Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber.

References

Julien J.-P.,et al.Biochim. Biophys. Acta 909:10-20(1987).
Perez-Olle R.,et al.J. Cell Sci. 115:4937-4946(2002).
Nusbaum C.,et al.Nature 439:331-335(2006).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Pospelov V.A.,et al.Cell Growth Differ. 5:187-196(1994).

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Discontinued
Cat# ALS16095
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