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UROD Antibody (Internal)
Goat Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | P06132 |
| Reactivity | Human |
| Host | Goat |
| Clonality | Polyclonal |
| Calculated MW | 41kDa |
| Dilution | ELISA (1:128000), IHC-P (5 µg/ml), WB (0.1-0.3 µg/ml) |
| Gene ID | 7389 |
|---|---|
| Other Names | Uroporphyrinogen decarboxylase, UPD, URO-D, 4.1.1.37, UROD |
| Target/Specificity | Human UROD |
| Reconstitution & Storage | Store at -20°C. Minimize freezing and thawing. |
| Precautions | UROD Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | UROD (HGNC:12591) |
|---|---|
| Function | Catalyzes the sequential decarboxylation of the four acetate side chains of uroporphyrinogen to form coproporphyrinogen and participates in the fifth step in the heme biosynthetic pathway (PubMed:14633982, PubMed:11069625, PubMed:21668429, PubMed:11719352, PubMed:18004775). Isomer I or isomer III of uroporphyrinogen may serve as substrate, but only coproporphyrinogen III can ultimately be converted to heme (PubMed:14633982, PubMed:11069625, PubMed:21668429, PubMed:11719352). In vitro also decarboxylates pentacarboxylate porphyrinogen I (PubMed:12071824). |
| Cellular Location | Cytoplasm. |
| Volume | 50 µl |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
References
Romeo P.-H.,et al.J. Biol. Chem. 261:9825-9831(1986).
Moran-Jimenez M.J.,et al.Am. J. Hum. Genet. 58:712-721(1996).
Mendez M.,et al.Submitted (FEB-1998) to the EMBL/GenBank/DDBJ databases.
Martinez di Montemuros F.,et al.Submitted (NOV-1998) to the EMBL/GenBank/DDBJ databases.
Martinez di Montemuros F.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
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