|Application ||WB, IHC-P, IF, ICC|
|Dilution||ICC (1:500-1:1000), IF (1:500-1:1000), IHC-P (1:100), WB (1:5000-1:10000) ,|
|Other Names||Spectrin alpha chain, non-erythrocytic 1, Alpha-II spectrin, Fodrin alpha chain, Spectrin, non-erythroid alpha subunit, SPTAN1, NEAS, SPTA2|
|Target/Specificity||Human SPTAN1 / Alpha Fodrin|
|Reconstitution & Storage||+4°C or -20°C, Avoid repeated freezing and thawing.|
|Precautions||SPTAN1 / Alpha Fodrin Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane.|
|Cellular Location||Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. Note=Expressed along the cell membrane in podocytes and presumptive tubule cells during glomerulogenesis and is expressed along lateral cell margins in tubule cells.|
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Provided below are standard protocols that you may find useful for product applications.
Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane.
Moon R.T.,et al.J. Biol. Chem. 265:4427-4433(1990).
Cianci C.D.,et al.Biochemistry 38:15721-15730(1999).
Kato S.,et al.Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases.
Totoki Y.,et al.Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
Humphray S.J.,et al.Nature 429:369-374(2004).
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