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UBE2G2 Antibody (clone 4D6)
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, IF |
|---|---|
| Primary Accession | P60604 |
| Reactivity | Human, Mouse, Rat, Monkey, Dog |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone Names | 4D6 |
| Calculated MW | 19kDa |
| Dilution | IF (1:100), IHC-P (10 µg/ml), WB (1:200-1:4000) |
| Gene ID | 7327 |
|---|---|
| Other Names | Ubiquitin-conjugating enzyme E2 G2, 6.3.2.19, Ubiquitin carrier protein G2, Ubiquitin-protein ligase G2, UBE2G2 |
| Target/Specificity | Human Ube2G2 |
| Reconstitution & Storage | Store at -20°C. Minimize freezing and thawing. |
| Precautions | UBE2G2 Antibody (clone 4D6) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | UBE2G2 (HGNC:12483) |
|---|---|
| Function | Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins (PubMed:20061386). In vitro catalyzes 'Lys-48'-linked polyubiquitination (PubMed:20061386). Involved in endoplasmic reticulum-associated degradation (ERAD) (PubMed:22607976). Required for sterol-induced ubiquitination of 3- hydroxy-3-methylglutaryl coenzyme A reductase and its subsequent proteasomal degradation (PubMed:23223569). |
| Cellular Location | Endoplasmic reticulum. Lipid droplet |
| Volume | 50 µl |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys- 48'-linked polyubiquitination. Involved in endoplasmic reticulum- associated degradation (ERAD).
References
Katsanis N.,et al.Genomics 51:128-131(1998).
Kalnine N.,et al.Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hattori M.,et al.Nature 405:311-319(2000).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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