|Application ||IHC-P, E|
|Dilution||ELISA (1:32000), IHC-P (5 µg/ml),|
|Other Names||Tubulin polyglutamylase TTLL4, 6.-.-.-, Tubulin--tyrosine ligase-like protein 4, TTLL4, KIAA0173|
|Reconstitution & Storage||Store at -20°C. Minimize freezing and thawing.|
|Precautions||TTLL4 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Polyglutamylase which preferentially modifies beta- tubulin and nucleosome assembly proteins NAP1 and NAP2. Involved in the side-chain initiation step of the polyglutamylation reaction rather than in the elongation step (By similarity).|
|Cellular Location||Cell projection, cilium. Cytoplasm, cytoskeleton, cilium basal body Note=Located in cilia. In some cells, also found in basal bodies (By similarity).|
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Provided below are standard protocols that you may find useful for product applications.
Polyglutamylase which preferentially modifies beta- tubulin and nucleosome assembly proteins NAP1 and NAP2. Involved in the side-chain initiation step of the polyglutamylation reaction rather than in the elongation step (By similarity).
Nagase T.,et al.DNA Res. 3:17-24(1996).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Mayya V.,et al.Sci. Signal. 2:RA46-RA46(2009).
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