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KRT20 / CK20 / Cytokeratin 20 Antibody (Asp409)

Rabbit Polyclonal Antibody

     
  • WB - KRT20 / CK20 / Cytokeratin 20 Antibody (Asp409) ALS16132
    Western blot of Cytokeratin 20 (D409) pAb in extracts from HeLa cells.
    detail
  • IHC - KRT20 / CK20 / Cytokeratin 20 Antibody (Asp409) ALS16132
    Anti-KRT20 / Cytokeratin 20 antibody IHC staining of human small intestine.
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
  • detail
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF
Primary Accession P35900
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 48kDa
Dilution IF (1:50-1:200), IHC-P (5 µg/ml), WB (1:500-1:1000)
Additional Information
Gene ID 54474
Other Names Keratin, type I cytoskeletal 20, Cytokeratin-20, CK-20, Keratin-20, K20, Protein IT, KRT20
Target/Specificity Human Cytokeratin 20 / Keratin 20
Reconstitution & Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
PrecautionsKRT20 / CK20 / Cytokeratin 20 Antibody (Asp409) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name KRT20
Function Plays a significant role in maintaining keratin filament organization in intestinal epithelia. When phosphorylated, plays a role in the secretion of mucin in the small intestine (By similarity).
Cellular Location Cytoplasm
Tissue Location Expressed predominantly in the intestinal epithelium. Expressed in luminal cells of colonic mucosa. Also expressed in the Merkel cells of keratinized oral mucosa; specifically at the tips of some rete ridges of the gingival mucosa, in the basal layer of the palatal mucosa and in the taste buds of lingual mucosa
Volume 50 µl
Research Areas
Citations (0)
citation

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Background

Plays a significant role in maintaining keratin filament organization in intestinal epithelia. When phosphorylated, plays a role in the secretion of mucin in the small intestine (By similarity).

References

Moll R.,et al.Differentiation 53:75-93(1993).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Zhou Q.,et al.J. Biol. Chem. 281:16453-16461(2006).
Calnek D.,et al.Differentiation 53:95-104(1993).
Moll R.,et al.J. Cell Biol. 111:567-580(1990).

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Discontinued
Cat# ALS16132
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