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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   ITLN1 / Omentin Antibody (aa27-168)   

ITLN1 / Omentin Antibody (aa27-168)

Rabbit Polyclonal Antibody

     
  • WB - ITLN1 / Omentin Antibody (aa27-168) ALS16133
    0
  • IHC - ITLN1 / Omentin Antibody (aa27-168) ALS16133
    Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q8WWA0
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 35kDa
Dilution ELISA (1:20000-1:80000), IHC-P (5 µg/ml), WB (1:1000-1:2000)
Additional Information
Gene ID 55600
Other Names Intelectin-1, ITLN-1, Endothelial lectin HL-1, Galactofuranose-binding lectin, Intestinal lactoferrin receptor, Omentin, ITLN1, INTL, ITLN, LFR
Target/Specificity Human ITLN1.
Reconstitution & Storage Store at -20°C for up to one year.
PrecautionsITLN1 / Omentin Antibody (aa27-168) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ITLN1
Synonyms INTL, ITLN, LFR
Function Has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes. Increases AKT phosphorylation in the absence and presence of insulin. May play a role in the defense system against microorganisms. May specifically recognize carbohydrate chains of pathogens and bacterial components containing galactofuranosyl residues, in a calcium-dependent manner. May be involved in iron metabolism.
Cellular Location Cell membrane; Lipid-anchor, GPI-anchor. Secreted Note=Enriched in lipid rafts. {ECO:0000250|UniProtKB:O88310}
Tissue Location Highly expressed in omental adipose tissue where it is found in stromal vascular cells but not in fat cells but is barely detectable in subcutaneous adipose tissue (at protein level). Highly expressed in the small intestine. Also found in the heart, testis, colon, salivary gland, skeletal muscle, pancreas and thyroid and, to a lesser degree, in the uterus, spleen, prostate, lymph node and thymus
Research Areas
Citations (0)

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Background

Has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes. Increases AKT phosphorylation in the absence and presence of insulin. May play a role in the defense system against microorganisms. May specifically recognize carbohydrate chains of pathogens and bacterial components containing galactofuranosyl residues, in a calcium-dependent manner. May be involved in iron metabolism.

References

Suzuki Y.A.,et al.Biochemistry 40:15771-15779(2001).
Lee J.K.,et al.Glycobiology 11:65-73(2001).
Tsuji S.,et al.J. Biol. Chem. 276:23456-23463(2001).
Chang B.Y.,et al.Comp. Biochem. Physiol. 137A:115-129(2004).
Yang R.-Z.,et al.Am. J. Physiol. 290:E1253-E1261(2006).

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$ 395.00
Cat# ALS16133
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