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S100A16 Antibody (aa1-50)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | Q96FQ6 |
| Reactivity | Human, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 12kDa |
| Dilution | ELISA (1:10000), IHC-P (5 µg/ml), WB (1:500-1:1000) |
| Gene ID | 140576 |
|---|---|
| Other Names | Protein S100-A16, Aging-associated gene 13 protein, Protein S100-F, S100 calcium-binding protein A16, S100A16, S100F |
| Target/Specificity | Detects endogenous levels of S100A16. |
| Reconstitution & Storage | Store at -20°C. |
| Precautions | S100A16 Antibody (aa1-50) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | S100A16 (HGNC:20441) |
|---|---|
| Synonyms | S100F |
| Function | Calcium-binding protein. Binds one calcium ion per monomer (PubMed:17030513). Can promote differentiation of adipocytes (in vitro) (By similarity). Overexpression in preadipocytes increases their proliferation, enhances adipogenesis and reduces insulin-stimulated glucose uptake (By similarity). |
| Cellular Location | Nucleus, nucleolus. Cytoplasm. Note=Primarily nucleolar. A high intracellular calcium level induces nucleolar exit and nucleocytoplasmic transport, whereas a low intracellular calcium level leads to nuclear translocation and accumulation within specific region of nucleoli (PubMed:17030513) |
| Tissue Location | Ubiquitous (PubMed:14684152). Highly expressed in esophagus, adipose tissues and colon. Expressed at lower level in lung, brain, pancreas and skeletal muscle. Expression is up-regulated in tumors of bladder, lung, thyroid gland, pancreas and ovary (PubMed:14684152). Expressed in astrocytes (PubMed:17030513) |
| Volume | 50 µl |
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Provided below are standard protocols that you may find useful for product applications.
Background
Calcium-binding protein. Binds one calcium ion per monomer.
References
Marenholz I.,et al.Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases.
Morita K.,et al.Submitted (JAN-2003) to the EMBL/GenBank/DDBJ databases.
Kim J.W.,et al.Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Gregory S.G.,et al.Nature 441:315-321(2006).
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