|Application ||WB, IHC-P, E|
|Dilution||ELISA (1:128000), IHC-P (5 µg/ml), WB (1-3 µg/ml)|
|Other Names||Membrane protein MLC1, MLC1, KIAA0027, WKL1|
|Target/Specificity||Human MLC1 / MLC. Reported variants represent identical protein: NP_631941.1, NP_055981.1.|
|Reconstitution & Storage||Store at -20°C. Minimize freezing and thawing.|
|Precautions||MLC1 / MLC Antibody (aa179-193) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Regulates the response of astrocytes to hypo-osmosis by promoting calcium influx.|
|Cellular Location||Membrane; Multi-pass membrane protein. Cell membrane. Cytoplasm, perinuclear region. Endoplasmic reticulum|
|Tissue Location||Expressed in the brain, with highest levels found in the amygdala, nucleus caudatus, thalamus and hippocampus|
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Provided below are standard protocols that you may find useful for product applications.
Regulates the response of astrocytes to hypo-osmosis by promoting calcium influx.
Meyer J.,et al.Mol. Psychiatry 6:302-306(2001).
Nomura N.,et al.DNA Res. 1:27-35(1994).
Nakajima D.,et al.DNA Res. 9:99-106(2002).
Collins J.E.,et al.Genome Biol. 5:R84.1-R84.11(2004).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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