|Application ||WB, IHC-P, E|
|Dilution||ELISA (1:10000-1:50000), IHC-P (15 µg/ml), WB (1:1000)|
|Other Names||Mesothelin, CAK1 antigen, Pre-pro-megakaryocyte-potentiating factor, Megakaryocyte-potentiating factor, MPF, Mesothelin, cleaved form, MSLN, MPF|
|Target/Specificity||Cross reactivity with homologues from other sources has not been tested.|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.|
|Precautions||MSLN / Mesothelin Antibody (Extracellular Domain, clone MN-1) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Membrane-anchored forms may play a role in cellular adhesion.|
|Cellular Location||Cell membrane; Lipid-anchor, GPI-anchor. Golgi apparatus Isoform 3: Secreted.|
|Tissue Location||Expressed in lung. Expressed at low levels in heart, placenta and kidney. Expressed in mesothelial cells. Highly expressed in mesotheliomas, ovarian cancers, and some squamous cell carcinomas (at protein level).|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Membrane-anchored forms may play a role in cellular adhesion.
Kojima T.,et al.J. Biol. Chem. 270:21984-21990(1995).
Chang K.,et al.Proc. Natl. Acad. Sci. U.S.A. 93:136-140(1996).
Muminova Z.E.,et al.BMC Cancer 4:19-19(2004).
Ho M.,et al.Clin. Cancer Res. 11:3814-3820(2005).
Daniels R.J.,et al.Hum. Mol. Genet. 10:339-352(2001).
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