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>   home   >   Products   >   Primary Antibodies   >   Cancer   >   MSLN / Mesothelin Antibody (Extracellular Domain, clone MN-1)   

MSLN / Mesothelin Antibody (Extracellular Domain, clone MN-1)

Mouse Monoclonal Antibody

     
  • WB - MSLN / Mesothelin Antibody (Extracellular Domain, clone MN-1) ALS16156
    Anti-Mesothelin Antibodies - Immunohistochemistry.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q13421
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names MN-1
Calculated MW 69kDa
Dilution ELISA (1:10000-1:50000), IHC-P (15 µg/ml), WB (1:1000)
Additional Information
Gene ID 10232
Other Names Mesothelin, CAK1 antigen, Pre-pro-megakaryocyte-potentiating factor, Megakaryocyte-potentiating factor, MPF, Mesothelin, cleaved form, MSLN, MPF
Target/Specificity Cross reactivity with homologues from other sources has not been tested.
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
PrecautionsMSLN / Mesothelin Antibody (Extracellular Domain, clone MN-1) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MSLN
Synonyms MPF
Function Membrane-anchored forms may play a role in cellular adhesion.
Cellular Location Cell membrane; Lipid-anchor, GPI-anchor. Golgi apparatus Isoform 3: Secreted.
Tissue Location Expressed in lung. Expressed at low levels in heart, placenta and kidney. Expressed in mesothelial cells. Highly expressed in mesotheliomas, ovarian cancers, and some squamous cell carcinomas (at protein level).
Research Areas
Citations (0)

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Background

Membrane-anchored forms may play a role in cellular adhesion.

References

Kojima T.,et al.J. Biol. Chem. 270:21984-21990(1995).
Chang K.,et al.Proc. Natl. Acad. Sci. U.S.A. 93:136-140(1996).
Muminova Z.E.,et al.BMC Cancer 4:19-19(2004).
Ho M.,et al.Clin. Cancer Res. 11:3814-3820(2005).
Daniels R.J.,et al.Hum. Mol. Genet. 10:339-352(2001).

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$ 395.00
Cat# ALS16156
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