|Application ||WB, IHC-P, E|
|Dilution||ELISA (1:100000-1:150000), IHC-P (10 µg/ml), WB (1:500)|
|Other Names||Plasminogen activator inhibitor 2, PAI-2, Monocyte Arg-serpin, Placental plasminogen activator inhibitor, Serpin B2, Urokinase inhibitor, SERPINB2, PAI2, PLANH2|
|Target/Specificity||Reactivity occurs against human PAI-2 protein. A BLAST analysis was used to suggest cross reactivity with PAI-2 proteins from several primates based on 94% homology with the immunizing sequence. Reactivity against homologues from other sources is not ...|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.|
|Precautions||SERPINB2 / PAI-2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Inhibits urokinase-type plasminogen activator. The monocyte derived PAI-2 is distinct from the endothelial cell- derived PAI-1.|
|Cellular Location||Cytoplasm. Secreted, extracellular space.|
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Provided below are standard protocols that you may find useful for product applications.
Inhibits urokinase-type plasminogen activator. The monocyte derived PAI-2 is distinct from the endothelial cell- derived PAI-1.
Ye R.D.,et al.J. Biol. Chem. 262:3718-3725(1987).
Schleuning W.-D.,et al.Mol. Cell. Biol. 7:4564-4567(1987).
Webb A.C.,et al.J. Exp. Med. 166:77-94(1987).
Antalis T.M.,et al.Proc. Natl. Acad. Sci. U.S.A. 85:985-989(1988).
Ye R.D.,et al.J. Biol. Chem. 264:5495-5502(1989).
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