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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   RARG / RAR-Gamma Antibody   

RARG / RAR-Gamma Antibody

Rabbit Polyclonal Antibody

     
  • IHC - RARG / RAR-Gamma Antibody ALS16194
    Anti-RARG / RAR-Gamma antibody IHC staining of human prostate.
  • WB - RARG / RAR-Gamma Antibody ALS16194
    Retinoic Acid Receptor gamma antibody detects RARG protein by Western blot analysis.
  • WB - RARG / RAR-Gamma Antibody ALS16194
    Retinoic Acid Receptor gamma antibody detects RARG protein by Western blot analysis.A.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P
Primary Accession P13631
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Calculated MW 50kDa
Dilution IHC-P (7.5 µg/ml), WB (1:500-1:3000),
Additional Information
Gene ID 5916
Other Names Retinoic acid receptor gamma, RAR-gamma, Nuclear receptor subfamily 1 group B member 3, RARG, NR1B3
Target/Specificity Human, mouse RARG
Reconstitution & Storage Aliquot and freeze at -20° C. Avoid freeze-thaw cycles.
PrecautionsRARG / RAR-Gamma Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RARG
Synonyms NR1B3
Function Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence of ligand, acts mainly as an activator of gene expression due to weak binding to corepressors. Required for limb bud development. In concert with RARA or RARB, required for skeletal growth, matrix homeostasis and growth plate function (By similarity).
Cellular Location Nucleus.
Volume 50 µl
Research Areas
Citations (0)

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Background

Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence of ligand, acts mainly as an activator of gene expression due to weak binding to corepressors. Required for limb bud development. In concert with RARA or RARB, required for skeletal growth, matrix homeostasis and growth plate function (By similarity).

References

Krust A.,et al.Proc. Natl. Acad. Sci. U.S.A. 86:5310-5314(1989).
Ishikawa T.,et al.Mol. Endocrinol. 4:837-844(1990).
Lehmann J.M.,et al.Nucleic Acids Res. 19:573-578(1991).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Scherer S.E.,et al.Nature 440:346-351(2006).

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$ 395.00
Cat# ALS16194
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