|Application ||WB, IHC-P, ICC|
|Reactivity||Human, Mouse, Rat|
|Dilution||ICC (1:100-1:1000), IHC-P (7.5 µg/ml), WB (1:1000-1:10000)|
|Other Names||Fumarate hydratase, mitochondrial, Fumarase, 220.127.116.11, FH|
|Target/Specificity||Human FH / Fumarase|
|Reconstitution & Storage||Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.|
|Precautions||FH / Fumarase / MCL Antibody (aa89-365) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Also acts as a tumor suppressor.|
|Cellular Location||Isoform Mitochondrial: Mitochondrion.|
|Tissue Location||Expressed in red blood cells; underexpressed in red blood cells (cytoplasm) of patients with hereditary non- spherocytic hemolytic anemia of unknown etiology|
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Also acts as a tumor suppressor.
Gellera C.,et al.Submitted (MAY-1996) to the EMBL/GenBank/DDBJ databases.
Bourgeron T.,et al.Submitted (FEB-1996) to the EMBL/GenBank/DDBJ databases.
Kalnine N.,et al.Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
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