|Application ||WB, IHC-P, ICC|
|Dilution||ICC (1:100-1:1000), IHC-P (7.5 µg/ml), WB (1:500-1:3000)|
|Other Names||Probable Xaa-Pro aminopeptidase 3, X-Pro aminopeptidase 3, 220.127.116.11, Aminopeptidase P3, APP3, XPNPEP3|
|Reconstitution & Storage||Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.|
|Precautions||XPNPEP3 Antibody (aa12-507) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides, such as Leu-Pro-Ala (PubMed:25609706, PubMed:28476889). Also shows low activity towards peptides with Ala or Ser at the P1 position (PubMed:28476889).|
|Cellular Location||Isoform 1: Mitochondrion Cytoplasm. Note=Mainly mitochondrial. Translocates to the cytoplasm following TNFRSF1B activation.|
|Tissue Location||Isoform 1 and isoform 2 are widely expressed, with isoform 1 being more abundant.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Collins J.E.,et al.Genome Biol. 5:R84.1-R84.11(2004).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Dunham I.,et al.Nature 402:489-495(1999).
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