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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   DDH / AKR1C1 Antibody (aa22-248)   

DDH / AKR1C1 Antibody (aa22-248)

Rabbit Polyclonal Antibody

     
  • WB - DDH / AKR1C1 Antibody (aa22-248) ALS16214
    Sample (30 ug whole cell lysate). A: Raji . 10% SDS PAGE. DDH / AKR1C1 antibody diluted at 1:1000
  • ICC - DDH / AKR1C1 Antibody (aa22-248) ALS16214
    Immunofluorescence of methanol-fixed A431 using AKR1C1 antibody at 1:200 dilution.
  • WB - DDH / AKR1C1 Antibody (aa22-248) ALS16214
    AKR1C1 antibody detects AKR1C1 protein by Western blot analysis.
  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, ICC
Primary Accession Q04828
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Calculated MW 37kDa
Dilution ICC (1:100-1:1000), IHC-P (7.5 µg/ml), WB (1:500-1:3000)
Additional Information
Gene ID 1645
Other Names Aldo-keto reductase family 1 member C1, 1.1.1.-, 20-alpha-hydroxysteroid dehydrogenase, 20-alpha-HSD, 1.1.1.149, Chlordecone reductase homolog HAKRC, Dihydrodiol dehydrogenase 1/2, DD1/DD2, High-affinity hepatic bile acid-binding protein, HBAB, Indanol dehydrogenase, 1.1.1.112, Trans-1, 2-dihydrobenzene-1, 2-diol dehydrogenase, 1.3.1.20, AKR1C1, DDH, DDH1
Target/Specificity Human DDH / AKR1C1
Reconstitution & Storage Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
PrecautionsDDH / AKR1C1 Antibody (aa22-248) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name AKR1C1
Synonyms DDH, DDH1
Function Converts progesterone to its inactive form, 20-alpha- dihydroxyprogesterone (20-alpha-OHP). In the liver and intestine, may have a role in the transport of bile. May have a role in monitoring the intrahepatic bile acid concentration. Has a low bile-binding ability. May play a role in myelin formation.
Cellular Location Cytoplasm.
Tissue Location Expressed in all tissues tested including liver, prostate, testis, adrenal gland, brain, uterus, mammary gland and keratinocytes. Highest levels found in liver, mammary gland and brain.
Volume 50 µl
Research Areas
Citations (0)

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Background

Converts progesterone to its inactive form, 20-alpha- dihydroxyprogesterone (20-alpha-OHP). In the liver and intestine, may have a role in the transport of bile. May have a role in monitoring the intrahepatic bile acid concentration. Has a low bile-binding ability. May play a role in myelin formation.

References

Stolz A.,et al.J. Biol. Chem. 268:10448-10457(1993).
Lou H.,et al.J. Biol. Chem. 269:8416-8422(1994).
Ciaccio P.J.,et al.J. Biol. Chem. 269:15558-15562(1994).
Khanna M.,et al.J. Steroid Biochem. Mol. Biol. 53:41-46(1995).
Nishizawa M.,et al.Genes Cells 5:111-125(2000).

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$ 395.00
Cat# ALS16214
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