|Application ||WB, IHC-P, ICC|
|Dilution||ICC (1:100-1:1000), IHC-P (7.5 µg/ml), WB (1:500-1:3000)|
|Other Names||Lactoylglutathione lyase, 18.104.22.168, Aldoketomutase, Glyoxalase I, Glx I, Ketone-aldehyde mutase, Methylglyoxalase, S-D-lactoylglutathione methylglyoxal lyase, GLO1|
|Target/Specificity||Human GLO1 / Glyoxalase I|
|Reconstitution & Storage||Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.|
|Precautions||GLO1 / Glyoxalase I Antibody (aa1-184) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. Involved in the regulation of TNF-induced transcriptional activity of NF- kappa-B. Required for normal osteoclastogenesis.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. Involved in the regulation of TNF-induced transcriptional activity of NF- kappa-B. Required for normal osteoclastogenesis.
Kim N.-S.,et al.J. Biol. Chem. 268:11217-11221(1993).
Ranganathan S.,et al.J. Biol. Chem. 268:5661-5667(1993).
Ridderstroem M.,et al.Biochem. J. 314:463-467(1996).
Ranganathan S.,et al.Gene 240:149-155(1999).
Totoki Y.,et al.Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.