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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   HT2A / TRIM32 Antibody (aa1-289)   

HT2A / TRIM32 Antibody (aa1-289)

Rabbit Polyclonal Antibody

     
  • IHC - HT2A / TRIM32 Antibody (aa1-289) ALS16228
    Anti-HT2A / TRIM32 antibody IHC staining of human testis.
  • WB - HT2A / TRIM32 Antibody (aa1-289) ALS16228
    TRIM32 antibody detects TRIM32 protein by western blot analysis.
  • WB - HT2A / TRIM32 Antibody (aa1-289) ALS16228
    TRIM32 antibody detects TRIM32 protein by western blot analysis.
  • SPECIFICATION
  • CITATIONS
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  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P
Primary Accession Q13049
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 72kDa
Dilution IHC-P (7.5 µg/ml), WB (1:500-1:20000),
Additional Information
Gene ID 22954
Other Names E3 ubiquitin-protein ligase TRIM32, 6.3.2.-, 72 kDa Tat-interacting protein, Tripartite motif-containing protein 32, Zinc finger protein HT2A, TRIM32, HT2A
Target/Specificity Human HT2A / TRIM32
Reconstitution & Storage Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
PrecautionsHT2A / TRIM32 Antibody (aa1-289) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TRIM32
Synonyms HT2A
Function Has an E3 ubiquitin ligase activity. Ubiquitinates DTNBP1 (dysbindin) and promotes its degradation. May ubiquitinate BBS2. May play a significant role in mediating the biological activity of the HIV-1 Tat protein in vivo. Binds specifically to the activation domain of HIV-1 Tat and can also interact with the HIV-2 and EIAV Tat proteins in vivo.
Cellular Location Cytoplasm. Note=Localized in cytoplasmic bodies, often located around the nucleus
Tissue Location Spleen, thymus, prostate, testis, ovary, intestine, colon and skeletal muscle
Volume 50 µl
Research Areas
Citations (0)

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Background

Has an E3 ubiquitin ligase activity. Ubiquitinates DTNBP1 (dysbindin) and promotes its degradation. May ubiquitinate BBS2. May play a significant role in mediating the biological activity of the HIV-1 Tat protein in vivo. Binds specifically to the activation domain of HIV-1 Tat and can also interact with the HIV-2 and EIAV Tat proteins in vivo.

References

Fridell R.A.,et al.Virology 209:347-357(1995).
Humphray S.J.,et al.Nature 429:369-374(2004).
Bienvenut W.V.,et al.Submitted (MAR-2009) to UniProtKB.
Dephoure N.,et al.Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
Locke M.,et al.Hum. Mol. Genet. 18:2344-2358(2009).

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$ 395.00
Cat# ALS16228
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