|Application ||WB, IHC-P|
|Reactivity||Human, Mouse, Rat|
|Dilution||IHC-P (10 µg/ml), WB (1:500-1:1000),|
|Other Names||Neutrophil defensin 4, Defensin, alpha 4, HNP-4, HP-4, DEFA4, DEF4|
|Target/Specificity||Human HNP-4 / DEFA4|
|Reconstitution & Storage||Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.|
|Precautions||HNP-4 / DEFA4 Antibody (Asp27) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Has antimicrobial activity against Gram-negative bacteria, and to a lesser extent also against Gram-positive bacteria and fungi. Protects blood cells against infection with HIV-1 (in vitro). Inhibits corticotropin (ACTH)-stimulated corticosterone production.|
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Has antimicrobial activity against Gram-negative bacteria, and to a lesser extent also against Gram-positive bacteria and fungi. Protects blood cells against infection with HIV-1 (in vitro). Inhibits corticotropin (ACTH)-stimulated corticosterone production.
Palfree R.G.E.,et al.Mol. Endocrinol. 7:199-205(1993).
Nusbaum C.,et al.Nature 439:331-335(2006).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Singh A.,et al.Biochem. Biophys. Res. Commun. 155:524-529(1988).
Wilde C.G.,et al.J. Biol. Chem. 264:11200-11203(1989).
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