|Application ||WB, IHC-P, E|
|Reactivity||Human, Mouse, Rat|
|Dilution||ELISA (1:10000), IHC-P (5 µg/ml), WB (1:500-1:1000)|
|Other Names||Monocarboxylate transporter 8, MCT 8, Monocarboxylate transporter 7, MCT 7, Solute carrier family 16 member 2, X-linked PEST-containing transporter, SLC16A2, MCT8, XPCT|
|Target/Specificity||SLC16A2 Antibodyantibody detects endogenous levels of SLC16A2.|
|Reconstitution & Storage||Store at -20°C.|
|Precautions||SLC16A2 / MCT8 Antibody (aa93-142) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Very active and specific thyroid hormone transporter. Stimulates cellular uptake of thyroxine (T4), triiodothyronine (T3), reverse triiodothyronine (rT3) and diidothyronine. Does not transport Leu, Phe, Trp or Tyr.|
|Cellular Location||Cell membrane; Multi- pass membrane protein|
|Tissue Location||Highly expressed in liver and heart.|
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Provided below are standard protocols that you may find useful for product applications.
Very active and specific thyroid hormone transporter. Stimulates cellular uptake of thyroxine (T4), triiodothyronine (T3), reverse triiodothyronine (rT3) and diidothyronine. Does not transport Leu, Phe, Trp or Tyr (By similarity).
Lafreniere R.G.,et al.Hum. Mol. Genet. 3:1133-1140(1994).
Kim D.,et al.Submitted (MAY-2002) to the EMBL/GenBank/DDBJ databases.
Ross M.T.,et al.Nature 434:325-337(2005).
Gauci S.,et al.Anal. Chem. 81:4493-4501(2009).
Visser W.E.,et al.Endocrinology 150:5163-5170(2009).
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