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DIXDC1 Antibody (clone 6B6)

Mouse Monoclonal Antibody

     
  • WB - DIXDC1 Antibody (clone 6B6) ALS16243
    Western blot of extracts (35 ug) from 9 different cell lines by using g anti-DIXDC1 monoclonal...
    detail
  • IF - DIXDC1 Antibody (clone 6B6) ALS16243
    Anti-DIXDC1 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently...
    detail
  • IHC - DIXDC1 Antibody (clone 6B6) ALS16243
    Anti-DIXDC1 antibody IHC staining of human kidney.
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF
Primary Accession Q155Q3
Reactivity Human, Monkey
Host Mouse
Clonality Monoclonal
Clone Names 6B6
Calculated MW 77kDa
Dilution IF (1:100), IHC-P (15 µg/ml), WB (1:200-1:2000)
Additional Information
Gene ID 85458
Other Names Dixin, Coiled-coil protein DIX1, Coiled-coil-DIX1, DIX domain-containing protein 1, DIXDC1, CCD1, KIAA1735
Target/Specificity Human DIXDC1
Reconstitution & Storage Store at -20°C. Minimize freezing and thawing.
PrecautionsDIXDC1 Antibody (clone 6B6) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name DIXDC1
Synonyms CCD1, KIAA1735
Function Positive effector of the Wnt signaling pathway; activates WNT3A signaling via DVL2. Regulates JNK activation by AXIN1 and DVL2.
Cellular Location Cell junction, focal adhesion. Cytoplasm, cytoskeleton, stress fiber. Cytoplasm Note=Colocalizes with gamma-tubulin at the centrosome, both during interphase and mitosis (PubMed:19375513). Associated with actin stress fiber at the filament ends (PubMed:16814745)
Tissue Location Ubiquitously expressed with higher expression in cardiac and skeletal muscles.
Volume 50 µl
Research Areas
Citations (0)
citation

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Background

Positive effector of the Wnt signaling pathway; activates WNT3A signaling via DVL2. Regulates JNK activation by AXIN1 and DVL2.

References

Wang X.,et al.Biochem. Biophys. Res. Commun. 347:22-30(2006).
Nagase T.,et al.DNA Res. 7:347-355(2000).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Taylor T.D.,et al.Nature 440:497-500(2006).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.

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Discontinued
Cat# ALS16243
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