|Application ||WB, IHC-P, IF|
|Dilution||IF (1:100), IHC-P (15 µg/ml), WB (1:200-1:2000)|
|Other Names||Dixin, Coiled-coil protein DIX1, Coiled-coil-DIX1, DIX domain-containing protein 1, DIXDC1, CCD1, KIAA1735|
|Reconstitution & Storage||Store at -20°C. Minimize freezing and thawing.|
|Precautions||DIXDC1 Antibody (clone 6B6) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Positive effector of the Wnt signaling pathway; activates WNT3A signaling via DVL2. Regulates JNK activation by AXIN1 and DVL2.|
|Cellular Location||Cytoplasm, cytosol. Note=Colocalizes with gamma-tubulin at the centrosome, both during interphase and mitosis Isoform 2: Cytoplasm.|
|Tissue Location||Ubiquitously expressed with higher expression in cardiac and skeletal muscles.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Positive effector of the Wnt signaling pathway; activates WNT3A signaling via DVL2. Regulates JNK activation by AXIN1 and DVL2.
Wang X.,et al.Biochem. Biophys. Res. Commun. 347:22-30(2006).
Nagase T.,et al.DNA Res. 7:347-355(2000).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Taylor T.D.,et al.Nature 440:497-500(2006).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
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